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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
G6PD
All Species:
52.12
Human Site:
T466
Identified Species:
81.9
UniProt:
P11413
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P11413
NP_000393.4
515
59257
T466
R
E
A
W
R
I
F
T
P
L
L
H
Q
I
E
Chimpanzee
Pan troglodytes
XP_001146640
398
44780
K351
D
G
E
G
E
A
T
K
G
Y
L
V
Y
T
T
Rhesus Macaque
Macaca mulatta
XP_001095273
515
59249
T466
R
E
A
W
R
I
F
T
P
L
L
H
Q
I
E
Dog
Lupus familis
XP_538209
545
62703
T496
R
E
A
W
R
I
F
T
P
L
L
H
K
I
E
Cat
Felis silvestris
Mouse
Mus musculus
Q00612
515
59244
T466
R
E
A
W
R
I
F
T
P
L
L
H
K
I
D
Rat
Rattus norvegicus
P05370
515
59357
T466
R
E
A
W
R
I
F
T
P
L
L
H
K
I
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505636
515
59203
T466
R
E
A
W
R
I
F
T
P
L
L
H
K
I
E
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080019
518
59674
T469
R
E
A
W
R
I
F
T
P
V
L
H
Q
L
E
Zebra Danio
Brachydanio rerio
XP_699168
523
59677
T474
R
E
A
W
R
I
F
T
P
L
L
H
Q
I
E
Tiger Blowfish
Takifugu rubipres
P54996
530
60451
T481
R
E
A
W
R
I
F
T
P
L
L
H
Q
I
E
Fruit Fly
Dros. melanogaster
P12646
524
60412
T471
R
E
A
W
R
I
F
T
P
I
L
H
Q
I
E
Honey Bee
Apis mellifera
XP_001121185
518
60246
Y430
E
T
E
L
D
L
T
Y
G
S
R
Y
K
D
L
Nematode Worm
Caenorhab. elegans
Q27464
522
60197
T474
E
Y
A
W
R
I
L
T
P
V
L
E
E
L
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FJI5
515
59098
T467
K
V
A
W
E
I
F
T
P
L
L
H
R
I
D
Baker's Yeast
Sacchar. cerevisiae
P11412
505
57503
T448
D
I
S
W
G
I
F
T
P
L
L
K
H
I
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67.9
99
87.8
N.A.
93.7
93.7
N.A.
90.2
N.A.
77.2
75.3
74.3
61.2
63.7
58.8
N.A.
Protein Similarity:
100
69.1
99.6
91.5
N.A.
97
96.6
N.A.
96.1
N.A.
89.7
85.8
82.6
74
76.8
74.9
N.A.
P-Site Identity:
100
6.6
100
93.3
N.A.
86.6
86.6
N.A.
93.3
N.A.
86.6
100
100
93.3
0
46.6
N.A.
P-Site Similarity:
100
6.6
100
100
N.A.
100
100
N.A.
100
N.A.
100
100
100
100
20
73.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
52.2
46.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
68.5
63.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
66.6
60
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
86.6
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
80
0
0
7
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
14
0
0
0
7
0
0
0
0
0
0
0
0
7
20
% D
% Glu:
14
67
14
0
14
0
0
0
0
0
0
7
7
0
60
% E
% Phe:
0
0
0
0
0
0
80
0
0
0
0
0
0
0
0
% F
% Gly:
0
7
0
7
7
0
0
0
14
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
74
7
0
0
% H
% Ile:
0
7
0
0
0
87
0
0
0
7
0
0
0
74
0
% I
% Lys:
7
0
0
0
0
0
0
7
0
0
0
7
34
0
7
% K
% Leu:
0
0
0
7
0
7
7
0
0
67
94
0
0
14
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
87
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
40
0
0
% Q
% Arg:
67
0
0
0
74
0
0
0
0
0
7
0
7
0
0
% R
% Ser:
0
0
7
0
0
0
0
0
0
7
0
0
0
0
0
% S
% Thr:
0
7
0
0
0
0
14
87
0
0
0
0
0
7
7
% T
% Val:
0
7
0
0
0
0
0
0
0
14
0
7
0
0
0
% V
% Trp:
0
0
0
87
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
0
0
0
0
0
7
0
7
0
7
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _